منابع مشابه
Statin therapy restores sympathovagal balance in experimental heart failure.
Inhibitors of hydroxymethylglutaryl-CoA reductase or statins have been shown to alleviate endothelial dysfunction. Their effects on constitutive nitric oxide synthase in the central nervous system may hypothetically affect the autonomic balance in sympathoexcitatory states, such as chronic heart failure (CHF). To address this issue, simvastatin (SIM) (0.3, 1.5, or 3 mg. kg-1. day-1 po) was give...
متن کاملCardiac resynchronization therapy in chronic heart failure.
Cardiac resynchronisation therapy (CRT) has emerged as a treatment option for patients with severe, drug-refractory heart failure and signs of intraventricular dyssynchrony. In clinical trials CRT reduced the overall mortality, improved symptoms, exercise tolerance, and left ventricular function, as compared with optimised medical therapy alone. One of the challenging fields in patient selectio...
متن کاملStem cell therapy for chronic heart failure.
PURPOSE OF REVIEW The aim of this review was to discuss recent advances in clinical aspects of stem cell therapy in heart failure with emphasis on patient selection, stem cell types and delivery methods. RECENT FINDINGS Several stem cell types have been considered for the treatment of patients with heart failure. In nonischemic heart failure, transplantation of CD34 cells improved myocardial ...
متن کاملEffects of Statin Therapy on Cardiac Sympathetic Nerve Activity and Left Ventricular Remodeling in Patients With Chronic Heart Failure
Statin therapy reduces enhanced cardiac sympathetic nerve activity (CSNA) in patients with heart disease, and prevents left ventricular (LV) remodeling in chronic heart failure (CHF) patients. We sought to evaluate the effects of statin therapy on CSNA, as evaluated by I-metaiodobenzylguanidine (MIBG) scintigraphy, and LV remodeling in CHF patients. This study was sub-analysis of our previous r...
متن کاملstatIN tHEraPY IN cHrONIc KIDNEY DIsEasE
Received for publication: May 22, 2007. Revised: Aug. 11, 2007. rEZUMat Department of Hemodialysis and Renal Transplantation, Victor Babes University of Medicine and Pharmacy, Timisoara
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2013
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-13-0314